Human GPR34 -Gi complex bound to S3E-LysoPS
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8xbe
Q-score: 0.445
Izume T, Kawahara R, Uwamizu A, Chen L, Yaginuma S, Omi J, Kawana H, Hou F, Sano FK, Tanaka T, Kobayashi K, Okamoto HH, Kise Y, Ohwada T, Aoki J, Shihoya W, Nureki O
Nat Commun (2024) 15 pp. 902-902 [ DOI: doi:10.1038/s41467-024-45046-z Pubmed: 38326347 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 34 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Bos taurus)
- Probable g-protein coupled receptor 34 (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Rattus norvegicus)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Human gpr34-gi complex bound to s3e-lysops (Complex)
- (2~{s})-2-azanyl-3-[[(2~{r})-1-ethoxy-3-[(~{z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid (551 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
Cryo-EM structure of adenosine receptor A3AR bound to CF101
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8x16
Q-score: 0.31
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ Pubmed: 38627384 DOI: doi:10.1038/s41467-024-47207-6 ]
- Piclidenoson (510 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
- Cryo-em structure of adenosine receptor a3ar bound to cf101 (160 kDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- G protein (Complex from Bos taurus)
- Scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
- G protein (Complex from Rattus norvegicus)
- A3ar (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
Cryo-EM structure of adenosine receptor A3AR bound to CF102
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8x17
Q-score: 0.473
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ Pubmed: 38627384 DOI: doi:10.1038/s41467-024-47207-6 ]
- Cryo-em structure of adenosine receptor a3ar bound to cf102 (160 kDa, Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- G protein (Complex from Bos taurus)
- A3ar (Complex from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Namodenoson (544 Da, Ligand)
- G protein (Complex from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
ETB-eGt complex bound to endothelin-1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xgr
Q-score: 0.425
Oshima HS, Sano FK, Akasaka H, Iwama A, Shihoya W, Nureki O
Biochem Biophys Res Commun (2024) 693 pp. 149361-149361 [ DOI: doi:10.1016/j.bbrc.2023.149361 Pubmed: 38128244 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,egt-alpha (48 kDa, Protein from Bos taurus)
- Endothelin-1 (2 kDa, Protein from Homo sapiens)
- Camelid antibody vhh fragment (17 kDa, Protein from Lama glama)
- Endothelin receptor type b (67 kDa, Protein from Homo sapiens)
- Complex of endothelin-1, etb, egt trimer and nb35* (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus rattus)
Phosphoinositide phosphate 3 kinase gamma bound with ADP and Gbetagamma
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8soc
Q-score: 0.337
Chen CL, Syahirah R, Ravala SK, Yen YC, Klose T, Deng Q, Tesmer JJG
Nat Struct Mol Biol (2024) [ Pubmed: 38565696 DOI: doi:10.1038/s41594-024-01265-y ]
- Phosphoinositide 3-kinase regulatory subunit 5 (98 kDa, Protein from Sus scrofa)
- Pi3k-gamma-adp bound with gbetagamma (210 MDa, Complex from Sus scrofa)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Bos taurus)
- Phosphatidylinositol-4,5-bisphosphate 3-kinase (127 kDa, Protein from Sus scrofa)
Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8sod
Q-score: 0.268
Chen CL, Syahirah R, Ravala SK, Yen YC, Klose T, Deng Q, Tesmer JJG
Nat Struct Mol Biol (2024) [ Pubmed: 38565696 DOI: doi:10.1038/s41594-024-01265-y ]
- Phosphoinositide 3-kinase regulatory subunit 5 (98 kDa, Protein from Sus scrofa)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Bos taurus)
- Phosphatidylinositol-4,5-bisphosphate 3-kinase (127 kDa, Protein from Sus scrofa)
- Pi3k-gamma-adp bound with two gbetagamma subunits in state 1 (210 MDa, Complex from Sus scrofa)
Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 2
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8soe
Q-score: 0.254
Chen CL, Syahirah R, Ravala SK, Yen YC, Klose T, Deng Q, Tesmer JJG
Nat Struct Mol Biol (2024) [ Pubmed: 38565696 DOI: doi:10.1038/s41594-024-01265-y ]
- Phosphoinositide 3-kinase regulatory subunit 5 (98 kDa, Protein from Sus scrofa)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Bos taurus)
- Pi3k-gamma-adp bound with two gbetagamma subunits in state 2 (210 MDa, Complex from Sus scrofa)
- Phosphatidylinositol-4,5-bisphosphate 3-kinase (127 kDa, Protein from Sus scrofa)
Cryo-EM structure of Long-wave-sensitive opsin 1
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8iu2
Q-score: 0.482
To Be Published
- Retinal (284 Da, Ligand)
- Long-wave-sensitive opsin 1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv recombinant human monoclonal antibody (scfv16) (27 kDa, Protein from Homo sapiens)
- Long-wave-sensitive opsin 1 (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
Resolution: 1.96 Å
EM Method: Single-particle
Fitted PDBs: 8xon
Q-score: 0.503
Xu X, Wang Y, Huang W, Li D, Deng Z, Long F
Mbio (2024) 15 pp. e0003124-e0003124 [ Pubmed: 38501868 DOI: doi:10.1128/mbio.00031-24 ]
- Atp-dependent clp protease proteolytic subunit (24 kDa, Protein from Streptomyces hawaiiensis)
- Clpp1,clpp2,clpc1,casein (Complex from Streptomyces hawaiiensis)
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Streptomyces hawaiiensis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Casein (2 kDa, Protein from Bos taurus)
- Ndp-hexose 4-ketoreductase (77 kDa, Protein from Streptomyces hawaiiensis)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
Resolution: 1.84 Å
EM Method: Single-particle
Fitted PDBs: 8xoo
Q-score: 0.514
Xu X, Wang Y, Huang W, Li D, Deng Z, Long F
Mbio (2024) 15 pp. e0003124-e0003124 [ Pubmed: 38501868 DOI: doi:10.1128/mbio.00031-24 ]
- Atp-dependent clp protease proteolytic subunit (24 kDa, Protein from Streptomyces hawaiiensis)
- Clpp1,clpp2,clpc1,casein (Complex from Streptomyces hawaiiensis)
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Streptomyces hawaiiensis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Casein (2 kDa, Protein from Bos taurus)
- Ndp-hexose 4-ketoreductase (77 kDa, Protein from Streptomyces hawaiiensis)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)